Allergic Respiratory Inflammation and Remodeling
نویسندگان
چکیده
منابع مشابه
Neurotrophins in chronic allergic airway inflammation and remodeling.
Allergic asthma is a chronic inflammatory disease characterized by the production of allergen-specific IgE antibodies, TH2 inflammation, airway hyperresponsiveness and airway remodeling. Airway remodeling represents the disease-limiting stage during disease progression, and the underlying cellular molecular network resulting in airway remodeling are still poorly defined. In addition to the well...
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BACKGROUND We previously observed that allergen-exposed mice exhibit remodeling of large bronchial-associated blood vessels. The aim of the study was to examine whether vascular remodeling occurs also in vessels where a spill-over effect of bronchial remodeling molecules is less likely. METHODS We used an established mouse model of allergic airway inflammation, where an allergic airway inflam...
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Studies of the initiation and maintenance of asthma and allergic inflammation implicate dysregulated interactions between mucosal epithelia and innate immune cells as the underlying cause of these disorders. The similarities of these responses with mucosal responses to parasitic intestinal worms may reveal pathways relevant to the perplexing rise of these chronic inflammatory disorders.
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The fine structure of collagen fibrils at sites of antigen-antibody interaction is described. Following injection of antigen (BSA or ferritin) into the center of the cornea of hyperimmune rabbits, an acidophilic ring of precipitate forms at the periphery of the cornea, where antigen and antibody interact in optimal proportions. The precipitate is soon removed by infiltrating polymorphs, but per...
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1Department of Medicine and Bioregulatory Sciences, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan 2Department of Molecular Cardiovascular Biology and Pharmacology, Ehime University Graduate School of Medicine, Shitsukawa, Ehime Tōon 791-0295, Japan 3Department of Cardiology, Nagoya University Graduate School of Medi...
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ژورنال
عنوان ژورنال: Turkish Thoracic Journal/Türk Toraks Dergisi
سال: 2015
ISSN: 2148-7197,2149-2530
DOI: 10.5152/ttd.2015.4942